Bibliografia

International Journal of Dentistry, Nov 2008

Massimo Politi, Corrado Toro, and Giulia Tenani

INTRODUCTION

It was Eagle in 1937 that first defined “stylalgia” as an autonomous entity related to abnormal length of the styloid process or to mineralization of the stylohyoid ligament complex [1–3].

The stylohyoid complex is made of styloid process, stylohyoid ligament, and the small cornus of the hyoid bone. All these structures are derivate from Reichert’s cartilage of the second branchial arch. The styloid process is an elongated conical projection of the temporal bone that lies anteriorly to the mastoid process, between the internal and external carotid arteries, and laterally the tonsillar fossa. In this space, the internal carotid artery, the internal jugular vein, the facial, glossopharyngeal, vagus, and hypoglossal nerves are located. From the styloid process, the stylohyoid, the styloglossal, and the stylopharyngeal muscles, and the stylohyoid and the stylomandibular ligaments originate [4, 5].

The normal length of the styloid process is individually variable, but in the majority of patients it is about 20 mm [6]. The incidence of Eagle’s syndrome varies among population, but the main incidence is 4% of the general population [2, 7]. Usually asymptomatic, it occurs in adult patients ranged from 30 to 50 years [5]. Females are affected more often thanmales [4]. Rarely, the anatomical condition is associated with cervical pain.

Eagle primarily described two syndromes [1]:

• Classic styloid syndrome: it frequently follows ton-sillectomy and is characterized by pharyngodynia localized in the tonsillar fossa and sometimes accom-panied by disphagia, odynophagia, hypersalivation, foreign body sensation, and more rarely by tempo-rary voice changes;
• The stylo-carotid syndrome: it is not correlated with In this condition, the stylohyoid appa-ratus compresses the internal and/or the external carotid arteries and especially their perivascular sympathetic fibers, resulting in a persistent pain irradiating in the carotid territory.

Pathogenesis is still being debated. Surgical trauma or local chronic irritation could cause osteitis and periosteitis of the stylohyoid complex with consequent reactive ossifying hyperplasia [1, 3]. The persistence of mesenchymal elements is able to produce osseous tissue in adults [8]. Residues of Reichert’s cartilage, as a consequence of trauma or mechan-ical stress during the development of the styloid process, can cause osseous metaplasia [9, 10]. The anatomic anomaly of the styloid process could be genetically transmitted as a recessive autosomal character [8]. Abnormal development of the styloid process is also associated with malformation of the atlanto-occipital hinge [11, 12]. Ossification of the stylohyoid ligament should be also related to endocrine disorders in postmenopausal women [13].

Eagle’s syndrome is treated surgically and nonsurgi-cally [14]. A pharmacological approach by transpharingeal infiltration of steroids or anesthetics in the tonsillar fossa has been used [15], but styloidectomy is the treatment of choice. Styloidectomy can be performed by an intra- or an extraoral approach [4, 16]. The intraoral approach may result in a restricted operative field, in the possibility of an incomplete control over many important vascular and nervous structures and in the risk of deep cervical infections. On the other hand, external surgical approach results in cutaneous scars, longer hospitalization, and risks of facial nerve injuries. The treatment’s choice usually depends on the experience of the surgeon.

Fig.1 – Preoperative CT scan showing elongation of the right styloid process.

Fig.2 -Intraoperative view of the surgical field. The distal third of the styloid process is completely exposed.

Fig.3 – 1 cm resected from the distal part of the styloid process.

REPORT OF A CASE

A 42-year-old female came to our Institution to evaluate pharyngodynia and foreign body sensation at the right sight of the throat for over 1 year. The patient was very compliant, and during the oropharingeal examination an elongated styloid process could be palpated intraorally posterior to the right tonsillar fossa. Palpation elicited painful sensation. The Orthopantomography showed the elongation of the right styloid process. For a complete study of the case, CT scans were taken for better defining length, angulation, and anatomical relationships of the styloid process. CT scans revealed a 3, 1 cm in length right styloid process (Figure 1). A diagnosis of Eagle’s classic styloid syndrome was made and an intraoral surgical treatment under general anesthesia was planned. During the surgical procedure the tip of the styloid process was identified by palpation. Due to the retruded position to the right tonsillar fossa, the tonsillectomy was not planned. The muscles of the pharyngeal wall were dissected, separated, and retracted. Then, an incision was made on the periosteum at the tip of the styloid process. The periosteum was stripped from the tip and the styloid process was exposed (Figure 2). 1 cm of his caudal part was excised (Figure 3) and the pharyngeal wall was sutured. Tonsillectomy was not required and haemorrhage did not occur. Amoxicillin was administered once preoperatively and once postoperatively. The patient was discharged on postoperative day 2. 1 year after surgery, the patient was symptom-free.

DISCUSSION

Patients with vague head and neck pain symptoms can lead to an extensive differential diagnosis [14]. Medical history is the main guide for the diagnosis of Eagle’s syndrome. The patient’s description of the symptoms is very important. Then, it is necessary to make a local examination palpating the tonsillar fossa, which should reveal a bony formation and should exacerbate pain aggravating symptoms with local ten-derness. Usually patients have temporary relief of symptoms from the local infiltration of lidocaine. Radiological exami-nation confirms the diagnosis: an orthopantomography and CT scans are required [4, 5, 7, 15].

Many factors can determine changes in the structure of the styloid process and it may vary in shape, position, and size [1, 3, 8, 13]. A wide variety of symptoms have been attributed to elongation of the styloid process [1].

Using CT scans is indicated for diagnosis, although also an accurate case history, local examination, and orthopanto-mography are required [4, 5, 7, 15]. The surgical treatment is the first choice in the literature [4, 15, 16]. When it is possible, the transoral approach is preferable. An intraoral approach results in a safe, simple, and less time consuming procedure than an extraoral approach and there is an absence of visible scars. We suggest the transoral approach in cases of Eagle’s syndrome with palpable styloid process.

When dealing with cases of cervical pain, the possibility of an Eagle syndrome should be considered.

REFERENCES

1. W. Eagle, “Elongated styloid process. Report of two cases,” Archives of Otolaryngology, vol. 25, pp. 584–587, 1937.
2. W. Eagle, “Elongated styloid process. Further observations and a new syndrome,” Archives of Otolaryngology, vol. 47, no. 5, pp. 630–640, 1948.
3. W. Eagle, “Symptomatic elongated styloid process: report of two cases of styloid process-carotid artery syndrome with operation,” Archives of Otolaryngology, vol. 49, no. 5, pp. 490– 503, 1949.
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12. Carella, “The stylohyoid apparatus and malformations of the atlo-occipital joint,” Acta Neurologica, vol. 26, no. 4, pp. 466–472, 1971.
13. Epifanio, “Processi stiloidei lunghi e ossificazione della catena stiloioidea,” Radiologia Pratica, vol. 12, pp. 127–132, 1962.
14. H. Mendelsohn, G. S. Berke, and D. K. Chhetri, “Het-erogeneity in the clinical presentation of Eagle’s syndrome,” Otolaryngology-Head and Neck Surgery, vol. 134, no. 3, pp. 389–393, 2006.
15. T. Evans and A. A. Clairmont, “The nonsurgical treatment of Eagle’s syndrome,” Eye, Ear, Nose & Throat Monthly, vol. 55, no. 3, pp. 94–95, 1976.
16. Buono, G. M. Mangone, A. Michelotti, F. Longo, and L. Califano, “Surgical approach to the stylohyoid process in Eagle’s syndrome,” Journal of Oral and Maxillofacial Surgery, vol. 63, no. 5, pp. 714–716, 2005.